THE CLINICAL COURSE OF COMORBID SUBSTANCE USE DISORDER AND ATTENTION DEFICIT/HYPERACTIVITY DISORDER: PROTOCOL AND CLINICAL CHARACTERISTICS OF THE INCAS STUDY

Abstract Background Substance use disorders (SUD) often co-occur with attention deficit hyperactivity disorder (ADHD).Although the short-term effects of some specific interventions have been investigated in randomized clinical trials, little is known about the long-term clinical course of treatment-seeking SUD patients with comorbid ADHD.Aims This

We investigate the behavior of a complex three-strain model with a generalized incidence rate.The incidence rate is an essential aspect of the model Immune System Support as it determines the number of new infections emerging.The mathematical model comprises thirteen nonlinear ordinary differential equations with susceptible, exposed, symptomatic,